Jump to
Anchor Menu Open
Anchor Menu Close

1. Button Set - Primary; Vertical; Spacer Options-XL/L/M/S; Authored-XL

2. Button Set - Primary; Horizontal; Spacer Options-XL/L/M/S; Authored-M

3. Button Set - Tertiary; Vertical; Spacer Options-XL/L/M/S; Authored-L

4. Button Set - Tertiary; Horizontal; Spacer Options-XL/L/M/S; Authored-S

5. Button Set | Link - Sitemap - Spacer 2XL

Categories 1

Category

Category

Category

Category

Please Note: The Button Set | Filter will be implemented along with Search feature. Hence it is not available for UAT currently.

test

See patient's infusion type

6. Button Selection Set/Group; Spacer Options-XL/L/M/S | Quiz Spacer-2XL/XL/L/M (Authored-XL)

  1. panel1
  2. panel2
  3. panel3
  4. panel4
  5. panel5
  6. panel6
  7. panel7
  8. panel8
  9. panel9

Question

Correct Answer

Subtitle

VMS can impact: Button Space S

Women living with VMS reported a negative impact on sleep (82%), mood (69%), concentration (69%), energy (63%), sexual activity (41%), work (46%), social activities (44%), and leisure activities (48%).1

Question

Correct Answer

How likely are severe VMS to cause a negative impact on overall quality of life compared to mild or moderate symptoms? Button Space XL

3.6x. Women with severe VMS were 3.58 times as likely to be negatively impacted as those with mild/moderate symptoms.1

Question

Correct Answer

VMS may be an indicator of future chronic conditions.Button Space L

True. Recent studies have shown that the frequency and severity of VMS can be used as a biomarker for chronic disease in the future, such as cognitive impairment, cardiovascular disease, and bone health.Severe. 

Question

Correct Answer

Waking up in the middle of the night due to VMS, feeling hot with a damp pillowcase, is classified as what severity of VMS?  Button Space M

Severe. A severe VMS episode is defined as the sensation of heat with sweating causing cessation of activity (such as sleeping)3

Question

Correct Answer

Sleep disturbances due to VMS are one of the most bothersome aspects of the menopausal transition.

True. 40% to 60% of women report sleep disturbances during the menopausal transition, including nighttime awakenings.4

Question

Correct Answer

VMS may be an indicator of future chronic conditions.Button Space L

True. Recent studies have shown that the frequency and severity of VMS can be used as a biomarker for chronic disease in the future, such as cognitive impairment, cardiovascular disease, and bone health.Severe. 

Question

Correct Answer

How long do women typically experience hot flashes and night sweats? 

Women experience VMS for a median duration of 7.4 years. However, some women may experience symptoms for 10 or more years.6

Question

Correct Answer

Approximately what percentage of women experience Vasomotor Symptoms (VMS), also known as hot flashes and night sweats, during the menopausal transition?

In the US, up to 80% of women experience VMS during the menopausal transition.3

Your Results

Congratulations! You answered  {totalCorrectAnswers} out of 8 questions correctly.

Let’s try that again. You answered {totalCorrectAnswers} out of 8 questions correctly.

Good effort. You answered {totalCorrectAnswers} out of 8 questions correctly.

7. Container Media Block - Spacer Options-2XL/XL/L/M; Authored-L

8. Reference List - Top & Bottom Spacer Options-XL/L/M/S; Authored-S

  1. Monteleone P, Mascagni G, Giannini A, Genazzani AR, Simoncini T. Symptoms of menopause - global prevalence, physiology and implications. Nat Rev Endocrinol 2018;14(4):199-215.
  2. Thurston RC. Vasomotor symptoms. In: Crandall CJ, Bachman GA, Faubion SS, et al., eds. Menopause Practice: A Clinician's Guide. 6th ed. Pepper Pike, OH: The North American Menopause Society, 2019;43-55.
  3. Padilla SL, Johnson CW, Barker FD, Patterson MA, Palmiter RD. A neural circuit underlying the generation of hot flushes. Cell Rep 2018;24(2):271-7.
  4. Krajewski-Hall SJ, Blackmore EM, McMinn JR, Rance NE. Estradiol alters body temperature regulation in the female mouse. Temperature 2018;5(1):56-69.
  5. Krajewski-Hall SJ, Miranda Dos Santos F, McMullen NT, Blackmore EM, Rance NE. Glutamatergic neurokinin 3 receptor neurons in the median preoptic nucleus modulate heat-defense pathways in female mice. Endocrinology 2019;160(4):803-16.

9. Button Set-Graphic; End-row variant; Spacer Options-2XL/XL/L/M; Authored-L

10. Card | Portrait; Spacer Options-2XL/XL/L/M; Authored-XL

The front of the Mechanism of VMS tool

Primary/Secondary Button Set - Secondary Colorway

Vertical Button Set 

The front of the Burden of VMS flashcard

Primary/Secondary Button Set - Secondary Colorway

Vertical Button Set

11. Card | Horizontal; Spacer Options-2XL/XL/L/M; Authored-L

12. Card | Offset; Spacer Options-2XL/XL/L/M; Authored-M

VMS in her words
  • Landscape
  • clinical efficacy
  • convenience

VMS in her words

MAT_ABC_NON_2023-00086

Burden of VMS brochure 4 column image

Diagnosis

Friday 11 17 2023 03:42 AM Thursday 11 30 2023 03:42 AM PST

Find out more about the impacts that VMS have on women. Oestrogen and neurokinin B (NKB) modulate KNDy neurons in a delicate balance, contributing to body temperature regulation.

Oestrogen and neurokinin B (NKB) modulate KNDy neurons in a delicate balance, contributing to body temperature regulation. KNDy neurons are stimulated by NKB and inhibited by oestrogen.1,2,3

  • Padilla SL, Johnson CW, Barker FD, Patterson MA, Palmiter RD.
  • A neural circuit underlying the generation of hot flushes. Cell Rep 2018;24(2):271-7.
  • 1.Krajewski-Hall SJ, Blackmore EM, McMinn JR, Rance NE.
  • 2.Krajewski-Hall SJ, Blackmore EM, McMinn JR, Rance NE.
  • 3.Krajewski-Hall SJ, Blackmore EM, McMinn JR, Rance NE.

13. Video Card & Video Feature; Spacer Options-2XL/XL/L/M; Authored-L

Watch Next

Test

Watch the Video here

Take a quiz about the most bothersome symptoms of menopause
Test

Watch the Video here

Take a quiz about the most bothersome symptoms of menopause
Test

Watch the Video here

Take a quiz about the most bothersome symptoms of menopause

14. Callout Block container; Spacer Options-2XL/XL/L/M; Authored-M

The burden of VMS

VMS in her words

Not an actual patient.

VMS in her words

MAT_ABC_NON_2023-00086

What really gets me about menopause is the hot flushes. Suddenly I'm turning red, and there's nothing I can do about it.

Women experience VMS for a median duration of 7.4 years. However, some women may experience symptoms for 10 or more years.8

15. Callout Block; Spacer Options-2XL/XL/L/M; Authored-XL

VMS in her words

Not an actual patient.

VMS in her words

MAT_ABC_NON_2023-00086

What really gets me about menopause is the hot flushes. Suddenly I'm turning red, and there's nothing I can do about it.

Women experience VMS for a median duration of 7.4 years. However, some women may experience symptoms for 10 or more years.8

16. Content Display/Illustration Set; Spacer Options-2XL/XL/L/M; Authored-2XL

test

Credible Treatment Information

test

Facts about diagnosis

test

Open & Honest Conversations

test

Open & Honest Conversations

17. Registration Callouts & validations; Spacer Options-2XL/XL/L/M

Please refer to the link: https://qa.astellaselement.astellasnewproduct.com/global-registration/registration

Please refer to the link: https://qa.astellaselement.astellasnewproduct.com/global-registration/registration

18. Thumbs-up-thumbs-down container; Spacer Options-XL/L/M/S; Authored-S

Was this content helpful?

19 & 20. Accordion-Spacer Options-2XL/XL/L/M; Authored-M

Table-Spacer Options (authored inside the Accordions)-2XL/XL/L/M; Authored-M & L

Table Inside Accordion

Treatment circle Safety done Efficacy home
Oestrogen therTreatmentapy close Adverse events include breast tenderness, vaginal bleeding, and bloating.
Includes a boxed warning that refers to stroke, deep vein thrombosis, endometrial cancer,† and dementia‡; oestrogen therapy should not be used for the prevention of cardiovascular disease or dementia circle		 Up to 75% reduction and significant reductions in severity done
Oestrogen-progestin therapy circle Adverse events include breast tenderness, vaginal bleeding, and bloating.
Includes a boxed warning that refers to stroke, deep vein thrombosis, pulmonary emboli, myocardial infarction, invasive breast cancer, and dementia‡; oestrogen therapy should not be used for the prevention of cardiovascular disease or dementi
Oestrogen combined with oestrogen agonist/antagonist Aevents include infection, pain, arthralgia, and headach.
Includes a boxed warning that refers to stroke, deep vein thrombosis, endometrial cancer,† dementia,‡ and use with additional oestrogen; oestrogen therapy should not be used for the prevention of cardiovascular disease or dementia
∗Concentration and Energy Activity Work Out Mental Stress
Content Concentration and Energy ©Copyright ™§ Tsst
Content

 Concentration and Energy
∗ 		 
Content

 Concentration and Energy   ©Table with Icons
Content

      
Content

      

∗Concentration and Energy€ closeActivity‡ circleWork Out ®Mental Stress
circleContenthome Concentration and Energy ©Copyright ™§ Tsst
Content

 Concentration and Energy
∗		 verified
Content

 Concentration and Energy done_all ©Table with Icons
Content

 done_all check check
Content

      
∗Concentration and Energycheck circleActivity Boldcircle  Work Out Mental Stress
Content Concentration and Energy -Bold  ©Copyright ™§ Tsst
Content

 checkConcentration check
∗		 done_outline
Content

 circleConcentration and Energycircle   ©Table with Icons
Content

      
Contentdone_outline

     done_outline

21. Core Form Container; Spacer Options-XL/L/M/S; Authored-L

Please refer to the link: https://qa.astellaselement.astellasnewproduct.com/forms-dropdown

22. Country Selector; Spacer Options-2XL/XL/L/M; Authored-2XL

Please refer to the link: https://qa.astellaselement.astellasnewproduct.com/country-selector

23. Feature Blocks; Spacer Options-2XL/XL/L/M; Authored-2XL

The burden of VMS

test

The Hypothalamus & VMS

Testing center alignment

Current Standard of Care

24. Hero 2; Spacer Options-2XL/XL/L/M

Please refer to the link: https://qa.astellaselement.astellasnewproduct.com/hero2-pick-a-boo

25. Hero 3; Spacer Options-2XL/XL/L/M

Please refer to the link: https://qa.astellaselement.astellasnewproduct.com/hero3/hero-3-variations-demo

26. Media Container; Spacer Options-2XL/XL/L/M; Authored-L

The burden of VMS

The Hypothalamus & VMS

Burden of VMS First Nav Title

Current Standard of Care

27. Page Container; Spacer Options-2XL/XL/L/M; Authored-XL

The front of the VMS survey tool

VMS survey tool

Use this survey to discuss with patients the current impact of VMS on their lives

The front of the Mechanism of VMS tool

Mechanism of VMS flashcard

Learn about the science behind VMS during the menopausal transition

The front of the Burden of VMS flashcard

Burden of VMS flashcard

Find out more about the impacts that VMS have on women

The front of the Mechanism of VMS tool

Mechanism of VMS flashcard

Learn about the science behind VMS during the menopausal transition

The front of the Burden of VMS flashcard

Burden of VMS flashcard

Find out more about the impacts that VMS have on women

The front of the VMS survey tool

VMS survey tool

Use this form with your patients to discuss the current impact and severity of their VMS

The front of the VMS survey tool

VMS survey tool

Use this survey to discuss with patients the current impact of VMS on their lives

The front of the Mechanism of VMS tool

Mechanism of VMS flashcard

Learn about the science behind VMS during the menopausal transition

The front of the Burden of VMS flashcard

Burden of VMS flashcard

Find out more about the impacts that VMS have on women

The front of the Mechanism of VMS tool

Mechanism of VMS flashcard

Learn about the science behind VMS during the menopausal transition

The front of the Burden of VMS flashcard

Burden of VMS flashcard

Find out more about the impacts that VMS have on women

The front of the VMS survey tool

VMS survey tool

Use this form with your patients to discuss the current impact and severity of their VMS

28. Button Set-Graphic; Inline variant; Spacer Options-L/M/S/XS; Authored-All

Custom Spacing
Custom Spacing

Title

SubTitle

Text

First Name is mandatoryinfo